ADMET for medicinal chemists : a practical guide / [edited by] Katya Tsaioun, Steven A. Kates

Includes bibliographical references and index

In silico ADME/tox predictions / David Lagorce ... [et al.] -- Absorption and physicochemical properties of the NCE / Jon Selbo and Po-Chang Chiang -- ADME / Martin E. Dowty ... [et al.] -- Pharmacokinetics for medicinal chemists / Leonid (Leo) Kirkovsky and Anup Zutshi -- Cardiac toxicity / Ralf Kettenhofen and Silke Schwengberg -- Genetic toxicity : in vitro approaches for medicinal chemists / Richard M. Walmsley and David Elder -- Hepatic toxicity / Jinghai James Xu and Keith Hoffmaster -- In vivo toxicological considerations / John P. Devine Jr. -- Preclinical candidate nomination and development / Nils Bergenhem -- Fragment-based drug design : considerations for good ADME properties / Haitao Ji